Nestled in the Rhodes Old Town district of Rhodes City, Casa Praxitelous Villa is within 13 minutes' walk of culture-oriented attractions like Archaeological Museum of Rhodes.

The Sephardic Kahal Kadosh Shalom Synagogue is at 750 metres from this Rhodes City villa, while Diagoras Stadium is a short distance away from this place. History fans will enjoy being near Castle Of The Old Town (900 metres) and Palace of the Grand Master of the Knights of Rhodes (1.4 km). There is Acropolis of Rhodes a 5-minute ride away, and KTEL bus station approximately a 10-minute walk from the hotel. Diagoras airport is at a distance of 20 minutes' journey by car.

Palace of the Grand Master of the Knights of Rhodes is situated within walking distance of Casa Praxitelous Villa.